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| 2008 Project of the Year |
| CF8C-Plus: New Cast Stainless Steel for High-Temperature Performance |
Oak Ridge National Laboratory
Dr. Philip J. Maziasz
Dr. D. Ray Johnson
Mr. Alexander G. DeTrana
CF8C-Plus is a low-cost, high-performance cast stainless steel. Its development was driven by the need for more performance and reliability in high-temperature exhaust components for advanced diesel and industrial gas turbine applications. The technology—developed by a team at Oak Ridge National Laboratory (ORNL) with Caterpillar, Inc.—is seen as being able to bridge the gap between cast iron, steel, and nickel-based superalloys to provide cost-effective performance and reliability upgrades for many applications, including advanced diesel engine and industrial gas turbine combustor or support components. full article

Shown L-R: Gary
Jones, DC Representative: Alex DeTrana, ORNL; Mark Reeves, Region
Coordinator; Edward Linsenmeyer, Past Chair FLC.
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| Improved Oxygen Management in Channel Catfish Hatcheries |
Agricultural Research Service (ARS) Mid South Area 
Mississippi State University 
Dr. Eugene L. Torrens (ARS)
Dr. James Steeby,
Mississippi State University
The largely family-owned and operated catfish hatcheries in the US have experienced financial stress during the past few years. One cause of this has been the extreme variability in hatch rates due to a number of factors, including variations in water quality, fungal and bacterial infections, fertility and so forth. Consequently, hatcheries have been challenged to increase efficiency without having to invest in expensive new infrastructure. full article

Shown L-R: Gary Jones, DC Representative; Dr. James Steeby, Mississippi State University; Mark Reeves, Region Coordinator; Dr. Eugene Torrens, ARS; Edward Linsenmeyer, Past Chair FLC.
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| Multiplexed Opsonophagocytic Assay (OPA) for Streptococcus pneumoniae |
Center for Disease Control & Prevention - Tech Transfer Office
Flow Applications, Inc. 
Dr. Joseph Martinez
Dr. Sandra Steiner
Dr. George Carlone
Mr. Tom O’Toole
Mr. Mike Hickey, Flow Applications, Inc.
Streptococcus pneumoniae remains one of the most significant causes of sickness and death worldwide and is a major cause of pneumonia, bacterial meningitis, and otitis media (ear infection)... To improve detection of these functional antibodies, CDC scientists developed a multiplexed opsonophagocytic assay which allows for detection of opsonic antibodies directed against multiple serotypes of S. pneumoniae using pneumococcal polysaccharide coated multicolor fluorescent beads. full article

Shown L-R: Gary Jones, DC Representative; Dr. Andrew Watkins, CDC; Dr. Mark Reeves, SE Region Coordinator; Edward Linsenmeyer, Past Chair FLC.
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| Chimeric Flavivirus Vaccines Based on Attenuated Dengue Type 2Virus |
Center for Disease Control & Prevention - Tech Transfer Office
Inviragen, Inc.
Dr. Clair Huang (Kinney) and Mr. Tom O’Toole of CDC
Dr. Richard Kinney and Dr. Dan Stinchcomb of Inviragen, Inc
Dengue (DF) and dengue hemorrhagic fever (DHF) are viral diseases caused by one of four closely related virus serotypes (DEN-1, DEN-2, DEN-3, and DEN-4), and are the most significant viral illnesses transmitted by mosquitoes to humans worldwide... There is a critical worldwide public health need for a dengue vaccine that successfully immunizes and protects humans against all four types of DEN virus... CDC has developed live-attenuated candidate DEN-1, DEN-2, DEN-3, and DEN-4 vaccine viruses that share three identical genetic mutations responsible for the non-virulent characteristics (attenuation determinants) of the vaccine viruses. full article

Shown L-R: Gary Jones, DC Representative; Dr. Andrew Watkins, CDC; Dr. Mark Reeves, SE Region Coordinator; Edward Linsenmeyer, Past Chair FLC.
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| Adaptive Band Excitation Method in Scanning Probe Microscopy |
Oak Ridge National Laboratory
Dr. Sergei V. Kalinin
Dr. Stephen Jesse
Mr. Alexander G. DeTrana
... standard SPM does not capture information about energy loss—information that is critically important in areas such as semiconductors and energy transport and storage. Classical SPMs methods based on lock-in or phase-locked loop detection are not well suited to the measurement of localized energy dissipation... ORNL researchers developed an improved capability for scanning probe microscopy—the Adaptive Band Excitation controller and software. This development has enabled a new family of SPM techniques that allow rapid measurements of energy dissipation in electrical, mechanical, magnetic, and thermal processes.
full article

Shown L-R: Gary
Jones, DC Representative: Alex DeTrana, ORNL; Mark Reeves, Region
Coordinator; Edward Linsenmeyer, Past Chair FLC.
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Dr. Mark Reeves
2008 Laboratory Representative of the Year |
Oak Ridge National Laboratory
Dr. Mark Reeves has served as Regional Coordinator of the FLC Southeast Region for the past four years, where he has provided consistent, thoughtful and creative leadership. His contributions to the FLC and to the Southeast Region, as well as to the Oak Ridge National Laboratory’s (ORNL) Office of Technology Transfer are many and substantial. full article
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